Research Associate - Phage Selections- Cambridge

Paramount Recruitment Ltd


Job ID :

13647


Company Type :

Staffing Firms


Industry :

Science and Research


Education Level :

Bsc,Master of Science,phD


Address 1 :

United Kingdom,--Cambridge,Cambridge,


Key Skills :

Molecular biology


Salary :

Negotiable


Date Posted :

27 Nov, 2018



Company Name :

Paramount Recruitment Ltd


Location1 :

Cambridge




Job Category :

Scientific Jobs


Experience :

Fresher


Job Type:

Permanent


Travel Amount:

negotiable





Description

Research Associate - Phage Selections- Cambridge

A fantastic opportunity has arisen for a Research Associate and a Senior Research Associate to join a leading and expanding life sciences company based in Cambridge. As an organisation they are developing a cutting-edge technology for a strong therapeutic product pipeline within oncology and inflammatory diseases.

You will join the Discovery Team and you will be responsible for carrying out new phage display selections, screening and characterisation of outputs in order to identify lead therapeutic candidates. Training and support will be provided by our experienced scientists, so this could be an excellent role for you if you are at an early stage in your scientific career.

Key Responsibilities
*Designing and performing target antigen quality control
*Design and generate random and/or rationally designed DNA display libraries for both naïve and affinity maturation.
*Execute manual or automated phage display panning against protein targets
*Characterize binding of phage candidates hits via SPR/BLI (Biacore or Octet), ELISA and cell-based assays.
*Sequence phage candidates and sub-clone into the appropriate protein expression system for small scale production and purification and further characterisation.
*Carry out affinity maturation library build and selections.
*Maintain a current and accurate laboratory record (lab notebook) of all activities
*There will also be opportunities to be involved in technology and process development

Required Experience:

* A BSc or MSc in biology/biochemistry/molecular biology/biotechnology
* Previous practical experience of working in a laboratory

Experience of some of the following:

* A good level of lab-based competency in molecular biology, manipulating DNA and/or creating expression constructs
* A good understanding of characterising protein-protein interactions by ELISA (experience of HTRF, cell binding assays and SPR/BLI would be a particular advantage)
* Experience of recombinant E.coli expression systems, protein purification and characterisation
* Experience of various in vitro display selection strategies
* Experience of working in the field of drug discovery
* Antibody or scaffold protein engineering

This is a superb opportunity to join a leading therapeutics company and in return they are offering a competitive salary and benefits package. For further information on this fantastic opportunity please contact myself, Lauren Gripton, at Paramount Recruitment, on lgripton@pararecruit.com.

Paramount Recruitment Limited provides services as an agency and an employment business. We regularly have similar roles in this area. Please see our website for details or send your CV in to us to find out the latest opportunities.


Company Name:

Paramount Recruitment Ltd


Headquarters:

No. 5 Lower Temple Street,No. 5 Lower Temple Street


Sector:

Staffing Firms


Country:

United Kingdom


Zipcode:

B1 1QU


Website:

www.paramountrecruitment.co.uk


Employees:

less than 100


Industry:

Pharmaceutical Recruitment


City:

Birmingham


Phone No. :

+44 (0)121 616 3460


Specialist in Permanent, Contract and Interim recruitment solutions to the Pharmaceutical and Life Science industries throughout Europe.

Our goal is to assist our candidates in finding that “perfect fit” between individual skills and experience and the right career opportunity. We identify and only present the positions that accurately reflect a chosen professional path. We discuss opportunities in detail, respect choices and ask permission prior to presenting any details to prospective clients. We brief and prepare every candidate for client meetings, and once the interview process is complete, provide feedback in a timely manner.

Our clients choose Paramount because:
• We are a Corporate Member of REC (Recently Inspected)
• We aspire to build long-term partnerships
• Our consultants are highly trained with expert market knowledge
• We are one of the most effective advertisers on the Internet
• We provide tailored Recruitment Solutions
• We keep up-to-date with Industry information – Salary scales, market knowledge, skills shortages

For more information,visit www.paramountrecruitment.co.uk.

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Established in January 2003, Paramount Recruitment is an independent recruitment consultancy which has grown to be one of the leading recruiters to the Healthcare, Pharmaceutical and Scientific industries, throughout the UK and Europe.

Our Vision is to be internationally recognised and admired as the number one recruitment solutions provider to the Healthcare Pharmaceutical and Scientific industries.

Our Mission is to employ the best Consultants, whose aim is to deliver a professional and superior service to ensure our clients achieve their business goals and our candidates attain their career aspirations.
 
Our Values define who we are as an organisation and what makes us different. They influence the way we work with each other – and the way we serve our clients and candidates:

  • Respect - Paramount people listen, engage and contribute to ensure we make  the best possible decisions.  We are proud to work in recruitment.  Our diversity    makes our team uniquely adaptable to whatever challenges be it location, industry or culture we work in.
  • Integrity - Credibility means everything.  We are honest and transparent in our approach with everyone.
  • Entrepreneurial - We make it our business to excel when others can’t.  We relish the opportunity of a challenge using innovative and unique solutions.  We strive to be the agency of choice.
  • Experts Continuous knowledge building and sharing is central to our success.  We work in partnership with clients and candidates, our combined knowledge of industry and recruitment ensures we match the right person to the right job at the right time.
  • Success – At Paramount we recognise and reward achievement, we nurture an environment where people can fulfil and maximise their potential.

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