Physical Chemistry Formulation Scientist

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Company Type :

Staffing Firms

Industry :


Education Level :


Address 1 :

United Kingdom,Kent,Sandwich,

Key Skills :

Formulation, physical chemistry

Salary :


Date Posted :

09 Nov, 2017

Company Name :

Search Consultancy

Location1 :


Job Category :

Pharma Research & Development Jobs

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Physical Chemistry Formulation Scientist
£27,000 - £32,000 per annum

My client, a pharmaceutical company based in Sandwich, is looking to recruit an enthusiastic and innovative Physical Chemistry Formulation Scientist to assist in the design, development and characterisation of Pharmaceutical dosage forms.

The purpose of this role is to participate alongside the client in the design, development and characterization of formulations. We are looking for candidates with both liquid dose (oral or parenteral) and solid dosage (immediate and modified release) to establish drug products of appropriate quality.

Job Responsibilities of the Physical Chemistry Formulation Scientist:
* Provide physical chemistry support utilizing chemical characterization techniques solubility, intrinsic dissolution rates, pKa, rates of degradation, equilibria and kinetics, salt and polymorph properties, salt selection and the Born Haber cycle analyzing reaction energies.
* Utilize basic physical chemistry and analytical techniques PXRD, DSC, simple crystallinity measurement and HPLC. Additionally, understanding of ternary phase diagrams and computational methods which provide the foundation of formulation design.
* To design and undertake high quality scientific experimentation to further the formulation and process development of dosage forms for novel drug candidates utilizing analytical / characterization activities to gain relevant data and drive formulation decisions.
* To design and interpret biorelevant dissolution studies in relation to pharmacokinetic data to predict dosage form performance.
* To interpret scientific data to derive clear conclusions and provide direction for future work and influence the development of quality drug products.
* To communicate effectively to the project team and present data at team meetings and also communicate cross functionally.
* To maintain high quality documentation of all activities in electronic notebooks, reports as required.
* Maintain awareness of technical advances in physical chemistry to develop innovative and novel solutions with sound scientific rationale.
Experience & Qualifications required for the Physical Chemistry Formulation Scientist:

* Degree in pharmaceutical or allied sciences (i.e. first degree in Pharmacy, Pharmaceutical Technology, Chemistry, Chemical Engineering, Life Sciences) or similar with relevant industrial experience. Alternatively a recent PhD will also be considered with relevant physical chemistry formulation and characterization experience.
* Practical work experience in an operational R&D role in pharmaceutical/drug delivery or allied industries with pre-formulation, formulation of pharmaceutical dosage forms.
* Broad scientific knowledge and technical ability with pre-formulation, formulation and characterization processing and characterization of pharmaceutical dosage forms.
* Good experimentalist with evidence of general competence in a range of laboratory skills/techniques as to support evaluation of pre-formulation, formulation of pharmaceutical dosage forms.
* Experience of computational bio-modelling, using packages such as GastroPlus or Simcyp to predict drug product performance.
* Good awareness/understanding of the requirements for working in a GCP and/or GMP environment, knowledge of drug development and formulation is essential
If you are an experienced Formulation Scientist with experience in Biorelevant Dissolution looking for a new challenge, then please apply now!

Search is an equal opportunities recruiter and we welcome applications from all suitably skilled or qualified applicants, regardless of their race, sex, disability, religion/beliefs, sexual orientation or age.

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