Downstream Processing Scientist- Antibodies- Reading

Paramount Recruitment Ltd

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Job ID :


Company Type :

Staffing Firms

Industry :

Science and Research

Education Level :

Bsc,Master of Science,phD

Address 1 :

United Kingdom,--Reading,Reading,

Key Skills :


Salary :


Date Posted :

15 Aug, 2018

Company Name :

Paramount Recruitment Ltd

Location1 :


Job Category :

Biotech Jobs

Experience :


Job Type:


Travel Amount:



Downstream Processing Scientist- Antibodies- Reading

A unique and exciting opportunity has arisen for a Downstream Processing Scientist- Antibodies to join an international biopharmaceutical company who are opening a brand new state-of-the-art manufacturing process development facility in Reading. As an organisation they are entering into a significant period of growth and investment to support the next phase of development for their innovative R&D pipeline.

The main responsibilities of the role are to perform downstream process development, optimisation and characterisation studies for antibody based production processes. The role is predominantly lab based and as the laboratory is newly established, there will be some involvement in supporting the setup of lab systems and procedures, equipment commissioning, preparing documentation and cross training in upstream and analytical procedures to support the broader team.

Key Duties:

*Support the technology transfer of downstream processes for bio-therapeutic products
and later externally to 3rd party contract manufacturer(s).
*Perform process development studies to increase process understanding, establish proven acceptable ranges, optimise performance and characterise/validate downstream unit operations.
*Purification techniques include;
Protein A affinity, ion exchange, hydrophobic interaction, mixed mode, hydroxyapatite chromatography, in column (and membrane) format.
Bench scale tangential, depth, sterile and virus (sizing) filtration studies.
*Perform in-process analytical tests as part of a larger team.
*Perform data analysis and interpretation, delivering internal, external presentations and
preparing reports suitable for GLP/GMP use and CMC submissions.
*Prepare other GLP/GMP documentation to support above activities, including SOPs, URSs, raw material/in-process specifications.
*General housekeeping, stock taking, ordering, laboratory cleaning, reagent/buffer prep.


*Bsc/MSc in Biological or Bio-Engineering discipline with 2 years+ of industry related
experience, preferably in therapeutic antibody process development
*Experience developing downstream processes suitable for GMP
*Experience executing downstream characterisation studies within BLA programs strongly
*Knowledge and experience of chromatography using AKTA systems (Pure/AVANT) and UNICORN software is essential.
*Experience performing and sizing sterile, depth, tangential and virus filtration steps.
*Understanding of protein characteristics and their influence on protein separation.
*Experience undertaking technology transfer into/out of companies preferred.

This is a fantastic opportunity to be involved in the set-up of a brand new facility and to really have an impact on the science, technical capabilities and laboratory output from the beginning. In return the company are offering a very competitive salary and benefits package. For further information on this superb opportunity please feel free to contact myself, Lauren Gripton of Paramount Recruitment,

Keywords- DSP, process development, downstream down-stream, processing, antibodies, antibody, protein, purification.

Paramount Recruitment Limited provides services as an agency and an employment business. We regularly have similar roles in this area. Please see our website for details or send your CV in to us to find out the latest opportunities.

Company Name:

Paramount Recruitment Ltd


No. 5 Lower Temple Street,No. 5 Lower Temple Street


Staffing Firms


United Kingdom


B1 1QU



less than 100


Pharmaceutical Recruitment



Phone No. :

+44 (0)121 616 3460

Specialist in Permanent, Contract and Interim recruitment solutions to the Pharmaceutical and Life Science industries throughout Europe.

Our goal is to assist our candidates in finding that “perfect fit” between individual skills and experience and the right career opportunity. We identify and only present the positions that accurately reflect a chosen professional path. We discuss opportunities in detail, respect choices and ask permission prior to presenting any details to prospective clients. We brief and prepare every candidate for client meetings, and once the interview process is complete, provide feedback in a timely manner.

Our clients choose Paramount because:
• We are a Corporate Member of REC (Recently Inspected)
• We aspire to build long-term partnerships
• Our consultants are highly trained with expert market knowledge
• We are one of the most effective advertisers on the Internet
• We provide tailored Recruitment Solutions
• We keep up-to-date with Industry information – Salary scales, market knowledge, skills shortages

For more information,visit

View all Paramount Recruitment Ltd Jobs

Established in January 2003, Paramount Recruitment is an independent recruitment consultancy which has grown to be one of the leading recruiters to the Healthcare, Pharmaceutical and Scientific industries, throughout the UK and Europe.

Our Vision is to be internationally recognised and admired as the number one recruitment solutions provider to the Healthcare Pharmaceutical and Scientific industries.

Our Mission is to employ the best Consultants, whose aim is to deliver a professional and superior service to ensure our clients achieve their business goals and our candidates attain their career aspirations.
Our Values define who we are as an organisation and what makes us different. They influence the way we work with each other – and the way we serve our clients and candidates:

  • Respect - Paramount people listen, engage and contribute to ensure we make  the best possible decisions.  We are proud to work in recruitment.  Our diversity    makes our team uniquely adaptable to whatever challenges be it location, industry or culture we work in.
  • Integrity - Credibility means everything.  We are honest and transparent in our approach with everyone.
  • Entrepreneurial - We make it our business to excel when others can’t.  We relish the opportunity of a challenge using innovative and unique solutions.  We strive to be the agency of choice.
  • Experts Continuous knowledge building and sharing is central to our success.  We work in partnership with clients and candidates, our combined knowledge of industry and recruitment ensures we match the right person to the right job at the right time.
  • Success – At Paramount we recognise and reward achievement, we nurture an environment where people can fulfil and maximise their potential.

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