Director, Recombinant Proteins Group

Lawrence Harvey

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Job ID :

15038


Company Type :

Staffing Firms


Industry :

Pharmaceuticals


Education Level :

PhD


Address 1 :

North America,--California,Redwood City,


Key Skills :

Recombinant proteins, crytalization, mammalian cell culture


Salary :

Negotiable


Date Posted :

19 Jun, 2019



Company Name :

Lawrence Harvey


Location1 :

Redwood City




Job Category :

Pharma Research & Development Jobs


Experience :

Fresher


Job Type:

Permanent


Travel Amount:

upto 15%





Description

Specific Responsibilities:
* Establish a high functioning protein production core group.
* Lead protein production group to generate antigens, antibodies, and cell-lines to facilitate discovery and project support.
* Utilize and develop novel technologies/methodologies to express and purify antigens (in addition to multi-transmembrane containing proteins).
* Guide scientists and team to address complex processes and transition leads into development.
* Interface with multiple discovery project and matrix teams across the organization.
* Excellent written and oral skills are necessary
* Accomplish goals under project team time lines

Requirements:
* Ph.D. in Biochemistry, Structural/Molecular Biology, or related field with 6-8 years' experience or 10+ years relevant experience.
* Extensive experience in leading a core group of scientists to make high quality proteins for in vitro and in vivo testing.
* Knowledge and experience in making antibodies from multiple species and technologies like bi-specifics, conjugation, and fusions is required.
* Demonstrated ability to make complex antigens like multi-transmembrane receptors, oligomers, and difficult to express and purify proteins.
* Demonstrated ability to generate proteins for crystallography and cryo-EM.
* Hands-on experience with multiple expression systems/formats (mammalian, insect, yeast, and E. coli) and purification media (affinity, ion-exchange, hydrophobic, size-exclusion chromatography) and automation is required.
* Experience in generating cell-lines (electroporation, viral transduction, etc.) is also required.
* Experience in evaluating protein liabilities and formulations is highly desirable.
* Excellent time management and organizational skills.
* Demonstrated ability to work in a multidisciplinary biologics discovery team.


Company Name:

Lawrence Harvey


Headquarters:

150 Leadenhall Street,London


Sector:

Staffing Firms


Country:

United Kingdom


Zipcode:

EC3V4TE


Website:

www.lawrenceharvey.com


Employees:

100 - 499


Industry:

Pharmaceutical Recruitment


City:

London


Phone No. :

0203 327 3072


Lawrence Harvey Life Sciences has exceptional relationships with the top talent and leading organisations in the Pharmaceutical and Medical Devices industry across the UK, USA, DACH region and the rest of Europe. Our consultants are experts within their specific areas and have a deep understanding of the full Life Sciences developmental cycle. As a client with a challenging role or a candidate with a niche specialism, you will receive a consultative service from people who truly understand the expectations and requirements of your industry. In an ever developing industry, an in-depth technical understanding and knowledge adds significant value and is imperative to ensuring our consultants are always up to speed, positioning ourselves perfectly to offer advice, analysis and support to our clients and candidates. We partner with leading pharmaceutical, medical device, generics, biotechnology, clinical research, R&D, manufacturing, regulatory affairs, CRO’s, CMO’s and medical communications organisations and have acquired an enviable and unrivalled reputation for delivering on niche, hard to fill and challenging positions. Our Specialisms within Life Sciences: Pharmaceuticals Medical Devices Regulatory Affairs Quality Assurance Quality Control Engineering Medical Affairs / Medical Information Qualified Persons Drug safety & Pharmacovigilance Biostatistics Clinical SAS Medical Writing Account Management & Business Development

For more information,visit www.lawrenceharvey.com.

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