Description
Conjugation Chemist (Antibody-Drug Conjugates)
£27,000 - £33,000 per Annum
London based, 12 month contract
Do you have a solid understanding of protein biochemistry?
Would you like to work for a leading Biotech company specialising in Antibody development?
My client are a London based Biotechnology company working at the cutting edge of Antibody Drug Discovery and Development, they are looking for a Conjugation Chemist to work in their R&D team to produce, purify and characterise a variety of protein conjugates including antibody-drug conjugates for supporting internal drug development and external partner collaborators.
Using their proprietary technology they have developed a generation of antibody drug congugates for oncology targets with marked improvements in terms of activity, ease of manufacture, therapeutic index and available quality control assays.
This is a laboratory based role, which would suit someone looking to grow their career within the Biopharmaceutuical sector with a leading technology based company.
Responsibilities of the role include;
* Produce, purify and characterise a variety of protein conjugates including antibody-drug conjugates
* Evaluate new drug-linkers by biophysical and chemical analysis of protein conjugates.
* Evaluate new conjugation methodologies and techniques.
* Perform routine maintenance on standard laboratory equipment.
* Work collaboratively with the Chemistry, Biology, Analytical teams and general larger organisation.
To be considered for the role, you will need the following skills & experience;
Essential:
* BSc, MSc or Ph.D. (or relevant research experience) in Biochemistry, Chemistry, Chemical Engineering, or related discipline
* Good understanding of chemistry and protein biochemistry
* Hand-on experience in chemical or biochemical laboratory
* Excellent communication skills, both written and spoken
* Good team-working skills, able to work under time constraints and to deadlines. Excellent timekeeping
* Consistently works to a high standard and looks for ways to improve current working practices and processes
Desirable:
* A track-record of protein modification experience
* Experience of protein analysis, characterisation and quantitation by UV/Vis spectroscopy, size-exclusion/hydrophobic interaction/ion exchange chromatography, HPLC, LCMS
* Experience of small molecule analysis, characterisation and quantitation by HPLC and LCMS
* Use of the AKTA system and Unicorn chromatography software
* Antibody-drug conjugates experience
* Competence in Microsoft Word, Excel, PowerPoint
* Strong interpersonal, influencing and collaboration skills, to work in a project-oriented, multi-disciplinary environment.
Key Words "Protein, Antibody, London, Conjugation Chemist, Research, R&D, Drug Discovery, Drug Development, HPLC, LC/MS, Protein analysis, Biochemist, Biochemistry, Lab, Laboratory"
Please apply online, call Neil Walton on 02030964706 or email neil.walton@srg.co.uk
The recruiter has stated that all applicants for this job should be able to prove they are legally entitled to work in the UK. SRG is a trading name of Science Recruitment Group Ltd an Employment Business/Agency. SRG, winners of the Recruitment Professional Awards 2011 'Best Company to work for' and 'Best People Development Business' awards, and the only "highly commended" company in the Annual Recruiter Awards for Excellence 2011, for 'Best Small Recruitment Agency to Work For'.
