Computational Chemist - 6-month contract - Berkshire

Paramount Recruitment Ltd

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Staffing Firms

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United Kingdom,Berkshire,Berkshire,

Key Skills :

Computer-aided Drug Design, Drug Discovery, Computational Chemist, Molecular Modelling, Small Molecu

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Date Posted :

31 Aug, 2018

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Paramount Recruitment Ltd

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Scientific Jobs

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Computational Chemist - 6-month contract - Berkshire

Computer-aided Drug Design, Drug Discovery, Computational Chemist, Molecular Modelling

Our client, a global biopharmaceutical leader, is looking to add to their highly skilled computational design team within Global Chemistry in Berkshire. We are looking for a contractor on an initial 6-month contract with the view to extend. This growing company transform the lives of people living with severe diseases, particularly in the areas of the central nervous system and immunology. Currently the business is investing more than 25% of revenue in cutting-edge scientific research to meet unmet patient needs.

This role requires an exceptional Computational Chemist to drive the discovery of new therapeutic candidates using targeted protein degradation. You will be specialised in compound design for early-stage drug discovery projects, and specialised in structure-based design and small molecules. This will be a fully office based position within the computational design department, and you will have interaction with a team of 5 lab chemists.

*Providing scientific leadership within your area of expertise
*Proactively anticipating project needs, contributing strategy and driving early project progression
*Creating effective working relationships within the global chemistry and the company matrix working environment
*Demonstrating high level of entrepreneurship and foster a can-do and can-win attitude
*Taking a lead in maintaining a safe and effective working environment by setting high personal standards and complying with all company codes of practice
Minimum requirements: -
*A PhD in molecular modelling or a related field is required with a good publications track record.
*Experienced practitioner of structure-based or ligand-based small molecule design.
*Basic understanding of modern medicinal chemistry.
*Ability to communicate effectively in English, both verbally and in writing, and skilled in communicating stories through data visualisations.
*Drug-ability/target evaluation.
*Working in the targeted protein degradation field.
*Experience in programming languages such as C++ and Python.
*The application of advanced statistics with R or Python etc.
*Knowledge of advanced molecular simulations approaches (examples of these packages are AMBER, GROMACS, ACEMD, NAMD, SIRE, Plumed, Desmond) and examples of applications to projects of significance to protein-ligand binding.
*Development of advanced cheminformatics protocols or applications using KNIME or coding toolkits such as RDkit, CDK or OpenEye.

Please send your CV and cover letter to or apply to this advert! An attractive hourly rate is on offer for this role and we are looking for someone to start ASAP.

Keywords: Computer-aided Drug Design, Drug Discovery, Computational Chemist, Molecular Modelling, Small Molecule, Berkshire, Contract, Biopharmaceutical, UK

Paramount Recruitment Limited provides services as an agency and an employment business. We regularly have similar roles in this area. Please see our website for details or send your CV in to us to find out the latest opportunities.

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